Mx. Zhao et al., Reaction of ketene aminals with aryl isothiocyanates - A simple route to isothiazole compounds, ACT CHIM S, 59(10), 2001, pp. 1763-1768
Cyclic and acyclic ketene aminals with different electron withdrawing group
s reacted with aryl isothiocyanates to give the corresponding alpha - carbo
n adducts in high yield which underwent oxidative cyclization with bromine
to afford isothiazole compounds in moderate yield.