Reaction of ketene aminals with aryl isothiocyanates - A simple route to isothiazole compounds

Citation
Mx. Zhao et al., Reaction of ketene aminals with aryl isothiocyanates - A simple route to isothiazole compounds, ACT CHIM S, 59(10), 2001, pp. 1763-1768
Citations number
10
Categorie Soggetti
Chemistry
Journal title
ACTA CHIMICA SINICA
ISSN journal
05677351 → ACNP
Volume
59
Issue
10
Year of publication
2001
Pages
1763 - 1768
Database
ISI
SICI code
0567-7351(2001)59:10<1763:ROKAWA>2.0.ZU;2-5
Abstract
Cyclic and acyclic ketene aminals with different electron withdrawing group s reacted with aryl isothiocyanates to give the corresponding alpha - carbo n adducts in high yield which underwent oxidative cyclization with bromine to afford isothiazole compounds in moderate yield.