PURPOSE: To evaluate the safety and outcome of laser in situ keratomileusis
in eyes with inactive herpetic keratitis.
METHODS: Prospective, interventional case series. In three eyes of three pa
tients with inactive unilateral herpetic keratitis for a minimum period of
I year, laser in situ keratomileusis was performed. Oral and topical acyclo
vir were prescribed perioperatively. No topical steroids were prescribed.
RESULTS: Preoperatively, all three eyes had corneal stromal scars with indu
ced astigmatism in two eyes and central stromal scar in one eye with best,c
orrected visual acuity of 20/120, 20/25, and 20/50, respectively. Postopera
tively, the three eyes achieved uncorrected visual acuity of 20/20, 20/20,
and 20/50, respectively, with decreased corneal scar. None of the patients
developed herpetic keratitis reactivation during a minimum follow-up of 6 m
onths.
CONCLUSION: Laser in situ keratomileusis was safe and effective in the trea
tment of refractive errors and corneal scars in three eyes of three patient
s with inactive herpetic keratitis. (C) 2001 by Elsevier Science Inc. All r
ights reserved.