Immunopathogenesis of hepatitis B e antigen negative chronic hepatitis B infection

Authors
Hadziyannis, SJ Vassilopoulos, D
Citation
Sj. Hadziyannis et D. Vassilopoulos, Immunopathogenesis of hepatitis B e antigen negative chronic hepatitis B infection, ANTIVIR RES, 52(2), 2001, pp. 91-98
Citations number
47
Categorie Soggetti
Microbiology
Journal title
ANTIVIRAL RESEARCH
ISSN journal
01663542 → ACNP
Volume
52
Issue
2
Year of publication
2001
Pages
91 - 98
Database
ISI
SICI code
0166-3542(200111)52:2<91:IOHBEA>2.0.ZU;2-T
Abstract
Hepatitis B e antigen (HBeAg) negative chronic hepatitis B represents curre ntly the predominant form of chronic hepatitis due to the hepatitis B virus (HBV) in several parts of the world. In this review, recent data regarding the process of HBeAg negative HBV strain selection during the course of ch ronic HBV infection are presented and the potential virus and/or host-media ted mechanisms that lead to chronic liver necroinflammation, i.e. chronic h epatitis are outlined. (C) 2001 Elsevier Science B.V. All rights reserved.