Identification of four additional myoinhibitory peptides (MIPs) from the ventral nerve cord of Manduca sexta

Authors
Blackburn, MB Jaffe, H Kochansky, J Raina, AK
Citation
Mb. Blackburn et al., Identification of four additional myoinhibitory peptides (MIPs) from the ventral nerve cord of Manduca sexta, ARCH INS B, 48(3), 2001, pp. 121-128
Citations number
31
Categorie Soggetti
Entomology/Pest Control","Biochemistry & Biophysics
Journal title
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
ISSN journal
07394462 → ACNP
Volume
48
Issue
3
Year of publication
2001
Pages
121 - 128
Database
ISI
SICI code
0739-4462(200111)48:3<121:IOFAMP>2.0.ZU;2-2
Abstract
Four new myoinhibitory peptides were isolated and identified from the ventr al nerve cord of adult Manduca sexta. The new peptides are related to two p reviously identified myoinhibitory peptides also isolated from adult M. sex ta, Alas-MIP I and Mas-MIP II. The sequences of the new peptides are APEKWA AFHGSWamide (Mas-MIP III), GWNDMSSAWamide (Mas-MIP IV), GWQDMSSAWamide (Mas -MIP V), and AWSALHGAWamide (Mas-MIP VI). Mas-MIPs III-VI were found to inh ibit spontaneous peristalsis of the adult M. sexta anterior hindgut (ileum) in vitro. Published 2001 Wiley-Liss, Inc.