Does satisfaction with abilities mediate the relationship between the impact of rheumatoid arthritis on valued activities and depressive symptoms?

Objective. Both impact of rheumatoid arthritis (RA) on valued life activiti es and dissatisfaction with abilities have been linked to depression among individuals with RA. We integrated these concepts by examining the hypothes is that satisfaction with one's abilities may explain the mechanism by whic h the impact of RA on valued activities leads to depression. Methods. Data were collected over 2 years (1997 and 1998) through interview s with the University of California, San Francisco, RA panel. Analyses exam ined whether activity impairment in 1997 predicted later (1998) dissatisfac tion with abilities and depression. Results. Greater impact on activities predicted dissatisfaction with abilit ies, which in turn was associated with higher depression scores. There was no direct relationship between activity impact and depression when satisfac tion with abilities was considered. Conclusion. Satisfaction with abilities mediated the relationship between t he impact of RA on valued activities and an increase in depressive symptoms , suggesting a need to assess not only physical decline but also individual s' interpretation of the decline.