Introduction: We examined whether the bedside SensiCath((R)) Blood Gas Moni
toring System could reduce both blood loss and the time needed to make vent
ilator-setting changes in a population of very low birth weight (VLBW; < 1,
500 g) infants. Material and Methods: A prospective, group sample trial was
conducted on ventilator-dependent newly born VLBW infants. The trial was u
nblinded due to the nature of the device and parental consent was obtained
before study enrollment. A total of 44 patients were studied. Results: Ther
e was no difference (mean SD) between the SensiCath group and controls with
respect to birth weight, gestational age, pH, PCO2, PO2 or Apgar at 5 min
(median 6, both groups). The amount of blood loss for arterial blood gas (A
BG) measurement alone was less in the SensiCath group compared to the contr
ol group (1.2 +/- 0 ml vs. 6.7 +/- 2.4 ml, p < 0.001) and the total blood l
oss was also less in the SensiCath group (8.1 +/- 5 ml vs. 10.5 +/- 6.3 ml,
p < 0.001), but there was no significant difference between each group in
the amount of blood transfused. The time to obtain ABG results and to make
a ventilator change was shorter in the SensiCath group compared to control
(2 +/- 0 vs. 26 +/- 21 min, p < 0.001). Discussion: Use of the modified Sen
siCath monitoring system permits near zero blood loss for ABG assessment an
d greatly reduces the time needed to make ventilator management decisions.
Copyright (C) 2001 S. Karger AG, Basel.