The proximity effect influences the transport properties of normal met
al-superconductor heterostructures. If these systems are small they ex
hibit pronounced charging effects. We show that charging suppresses th
e proximity effect. The effect can be made visible since the charging
energy and hence the proximity effect can be modulated by gate voltage
s. We derive these results in a unified formulation which also describ
es single electron tunneling, Andreev reflection and the supercurrent
through normal-superconductor systems in the presence of charging effe
cts.