DNA diagnosis in hereditary nephropathies

Citation
K. Zerres et al., DNA diagnosis in hereditary nephropathies, CLIN NEPHR, 56(3), 2001, pp. 181-192
Citations number
6
Categorie Soggetti
Urology & Nephrology","da verificare
Journal title
CLINICAL NEPHROLOGY
ISSN journal
03010430 → ACNP
Volume
56
Issue
3
Year of publication
2001
Pages
181 - 192
Database
ISI
SICI code
0301-0430(200109)56:3<181:DDIHN>2.0.ZU;2-A
Abstract
Increasing knowledge regarding the genetic basis of hereditary nephropathie s has contributed much to the understanding of their pathogenesis. In addit ion, localization and identification of genes have offered new tools for th e classification and diagnostics of hereditary nephropathies. The diagnosis at the DNA level, however, differs from classical diagnostic procedures in many respects. The current status of DNA diagnostics in hereditary nephrop athies is summarized in this review, which includes a discussion of the maj or principles and limitations.