Meningitis and endocarditis caused by group B streptococcus in a human immunodeficiency virus (HIV) infected patient

We present a case of meningitis and endocarditis caused by Streptococcus ag alactiae (group B streptococcus) in an adult patient with human immunodefic iency virus (HIV) infection. To our knowledge, only four other cases of men ingitis, none of which had concomitant endocarditis, have been reported so far. A 45-year-old homosexual patient presented with fever, confusion, and signs of meningeal irritation. Streptococcus agalactiae was cultured from t he blood, urine, and cerebrospinal fluid (CSF). Diagnosis of meningitis cau sed by streptococcus agalactiae was made. On day 35, a heart murmur was not iced, and patient developed cardiac decompensation. Echocardiography reveal ed vegetations on the mitral and aortic valve. After nine weeks of antibiot ic treatment, the patient was discharged from the hospital in good general condition, with improved CSF and echocardiographic findings.