Order out of complexity - protein structures that interact with heparin

Authors
Mulloy, B Linhardt, RJ
Citation
B. Mulloy et Rj. Linhardt, Order out of complexity - protein structures that interact with heparin, CURR OP STR, 11(5), 2001, pp. 623-628
Citations number
46
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN STRUCTURAL BIOLOGY
ISSN journal
0959440X → ACNP
Volume
11
Issue
5
Year of publication
2001
Pages
623 - 628
Database
ISI
SICI code
0959-440X(200110)11:5<623:OOOC-P>2.0.ZU;2-U
Abstract
Many proteins of widely differing functionality and structure are capable o f binding heparin. Structural characterisations of the many types of such c omplexes are being reported in ever-increasing number and at improved resol ution. Several crystal structures of complexes formed through the interacti on of heparin-derived oligosaccharides with one or more protein partners ha ve been described.