The survival rate of hemodialysis patients with autosomal dominant polycystic kidney disease: A multicenter study

The aim of this study was to investigate the survival rate of hemodialysis (HD) patients suffering from autosomal dominant polycystic kidney disease ( ADPKD) who were being treated in the five renal units of Northern Greece. S eventy-nine ADPKD patients with end-stage renal disease (ESRD), and 66 ESRD patients suffering from glomerulonephritis (GN), were included in the stud y; the groups were comparable with regard to age and sex. There were no sta tistical differences between the two groups with regard to the age at which they started HD or the presence of hypertension, angina pectoris, or heart failure. There was no significant difference in the survival rate between the two groups, and the survival rate between the two groups was independen t of the presence of hypertension, angina pectoris, or heart failure. The s urvival rates in the 1st, 3rd, 5th, 7th, and 9th year on HD in patients suf fering from ADPKD were 98%, 82%, 54%, 35%, and 23%, respectively, which wer e comparable to those of patients suffering from GN (96%, 82%, 54%, 35%, an d 23%, respectively). The primary causes of death in the two groups were ca rdiovascular events and electrolyte disorders. We conclude that the surviva l rate of HD patients suffering from ADPKD is not different from that of HD patients suffering from GN, and that survival in these, two groups is inde pendent of the presence of hypertension, angina pectoris, or heart failure.