Clinical applications of bone graft substitutes in spine surgery: consideration of mineralized and demineralized preparations and growth factor supplementation
S. Berven et al., Clinical applications of bone graft substitutes in spine surgery: consideration of mineralized and demineralized preparations and growth factor supplementation, EUR SPINE J, 10, 2001, pp. S169-S177
Bone graft substitutes may be broadly classified as mineralized and deminer
alized preparations. This article reviews the basic science and biology und
erlying each preparation. A review of the clinical and experimental applica
tions of each preparation follows. The text concludes with a review of grow
th factors as biological supplements.