Sequence structure of 12 novel Y chromosome microsatellites and PCR amplification strategies

In this work, we present sequencing data for 12 recently reported Y STR loc i (DYS434. DYS435, DYS436, DYS437, DYS438, DYS439, GATA A10, GATA 7.1. GATA 7.2, GATA C4, GATA H4, GATA A4), as well as the PCR multiplex strategies w e implemented for their detection. Sequenced allelic ladders were constructed and a nomenclature for these new systems is proposed based on the sequence structure and following ISFG rec ommendations. GATA A4 and DYS439 are likely the same STR. They have the same STIR structu re and the alleles are always the same in the same individuals. Sequence polymorphisms were observed in the GATA C4 and DYS437 STRs. The va riation in DYS437 was associated with a specific population group and is ve ry interesting not only for forensic genetics but also for anthropological studies. (C) 2001 Elsevier Science Ireland Ltd, All rights reserved.