To determine whether motor development in premature infants varies accordin
g to sleep position, we evaluated 213 infants < 1750 g birth weight enrolle
d in the Collaborative Home Infant Monitoring Evaluation (CHIME). At 56 wee
ks postconceptional age (PCA), sleep position was determined by maternal re
port, and the Bayley Scales of Infant Development 2nd Edition (BSID-II) wer
e performed. Infants who slept supine were less likely than infants who sle
pt prone to receive credit for maintaining the head elevated to 45 degrees
(p = .021), and infants who slept nonprone were less likely than prone slee
pers to receive credit for maintaining the head elevated to 90 degrees and
lowering with control (p = .001). The Psychomotor and Mental Development In
dices at 56 and 92 weeks PCA were not altered by usual sleep position at 56
weeks PCA. In summary, infants sleeping supine are less able to lift the h
ead and lower with control at 56 weeks PCA, but global developmental status
was unaffected. Supine sleeping has been associated with decreased risk fo
r sudden infant death syndrome, but compensatory strategies while awake may
be needed to avoid delayed acquisition of head control.