To obtain a reference DNA profile from a missing person, we analyzed a vari
ety of personal effects, including two lip cosmetics, both of which gave fu
ll DNA profiles. Further investigations were undertaken to explore this pre
viously unreported source of DNA. We have tested a range of brands and type
s of lip cosmetics. Our studies have revealed that lip cosmetics are an exc
ellent source of DNA, with almost 80% of samples giving a result. However,
artifacts are frequently observed in the DNA profiles when Chelex is used f
or the DNA extraction and additional DNA purification procedures are requir
ed to ensure that an accurate DNA profile is obtained.