We report an atypical lipoma arising in the tongue of a 43-year-old man who
presented with an indolent dorsal lingual swelling. Atypical lipomas conta
in multivacoulated lipoblasts, which distinguishes them from benign lipomas
. The superficial location in this case distinguishes this tumour from well
-differentiated liposarcoma, which is biologically similar in lacking the p
ropensity for metastasis. The superficial location of atypical lipoma allow
s a complete resection, which is often not possible for the deep-seated cou
nterpart. Atypical lipoma and well-differentiated liposarcoma, if left in s
itu, may undergo transition to de-differentiated liposarcoma. Atypical lipo
ma should be completely excised with a cuff of normal tissue in order to pr
event repeated local recurrence and the possibility of de-differentiation.