Antifeedant rings B and D opened limonoids from Khaya senegalensis

Three new rings B and D opened limonoids, two mexicanolides named khayanone (1) and 2-hydroxy-seneganolide (2) and one rearranged phragmalin limonoid of 1-O-acetylkhayanolide A (3), were isolated together with six known B,D-s eco compounds from the acetone extract of the stem bark of Khaya senegalens is. Structures of new compounds were elucidated by spectroscopic means, and the absolute stereochemistry of 1 was established by CD study of the diben zoate derivative. The insect antifeedant and antiviral activities of the ne w compounds were also determined.