Polyacetylene carboxylic acids from Mitrephora celebica

Authors
Zgoda, JR Freyer, AJ Killmer, LB Porter, JR
Citation
Jr. Zgoda et al., Polyacetylene carboxylic acids from Mitrephora celebica, J NAT PROD, 64(10), 2001, pp. 1348-1349
Citations number
8
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
10
Year of publication
2001
Pages
1348 - 1349
Database
ISI
SICI code
0163-3864(200110)64:10<1348:PCAFMC>2.0.ZU;2-#
Abstract
A new polyacetylene carboxylic acid, 13(E),17-octadecadiene-9,11-diynoic ac id (13,14-dihydrooropheic acid, 1), and the known 17-octadecene-9,11,13-tri ynoic acid (oropheic acid, 2) were isolated from the stem bark of Mitrephor a celebica through bioassay-guided fractionation. Both compounds demonstrat ed significant activity against methicillin-resistant Staphylococcus aureus and Mycobacterium smegmatis.