Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa

Authors
Casapullo, A Cutignano, A Bruno, I Bifulco, G Debitus, C Gomez-Paloma, L Riccio, R
Citation
A. Casapullo et al., Makaluvamine P, a new cytotoxic pyrroloiminoquinone from Zyzzya cf. fuliginosa, J NAT PROD, 64(10), 2001, pp. 1354-1356
Citations number
12
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
10
Year of publication
2001
Pages
1354 - 1356
Database
ISI
SICI code
0163-3864(200110)64:10<1354:MPANCP>2.0.ZU;2-M
Abstract
A new pyrroloiminoquinone alkaloid (1) belonging to the makaluvamine family has been isolated from the sponge Zyzzya cf. fuliginosa collected in the w aters off the Vanuatu Islands. The compound, designated makulavamine P, was characterized on the basis of its spectral data and displayed cytoxicity i n the muM range on KB cells and antioxidant activity.