The first two patients with dura mater associated Creutzfeldt-Jakob disease in the Netherlands

Creutzfeldt-Jakob disease (CJD) can be transmitted through human growth hor mone or gonadotrophin administration, dura mater or cornea transplantation, depth EEG monitoring and the use of contaminated neurosurgical instruments . We describe the first two dura mater associated CID cases in the Netherla nds. Ten and fourteen years before the onset of symptoms both patients rece ived a Lyodura implantation. Findings are discussed in light of the growing epidemic of CID among dura mater recipients.