The new optical criterion for objective diagnosis of malignant tumors in hu
man beings and animals tissues is suggested. The molecules of NLC thin laye
rs on sections of malignant tissues have a homeotropic orientation, while o
n the surface of benign and normal tissues the orientation is almost planar
or tilted. Therefore malignant tumors in light microscope with crossed pol
arizer and analyzer always looks black. The different orientation of NLC mo
lecules is explained by two orders different value of anchoring energy on t
he surface of malignant and benign tissues. The experiments on contact angl
es measurement of NLC and H2O droplets on investigated surfaces proved the
difference in their surface tension that also confirm authenticity of a new
criterion for microscopic malignancies' identification.