New criterion on cancer detection based on NLC orientation

Citation
Mg. Tomilin et al., New criterion on cancer detection based on NLC orientation, MOLEC CRYST, 367, 2001, pp. 2921-2929
Citations number
11
Categorie Soggetti
Physical Chemistry/Chemical Physics
Volume
367
Year of publication
2001
Pages
2921 - 2929
Database
ISI
SICI code
Abstract
The new optical criterion for objective diagnosis of malignant tumors in hu man beings and animals tissues is suggested. The molecules of NLC thin laye rs on sections of malignant tissues have a homeotropic orientation, while o n the surface of benign and normal tissues the orientation is almost planar or tilted. Therefore malignant tumors in light microscope with crossed pol arizer and analyzer always looks black. The different orientation of NLC mo lecules is explained by two orders different value of anchoring energy on t he surface of malignant and benign tissues. The experiments on contact angl es measurement of NLC and H2O droplets on investigated surfaces proved the difference in their surface tension that also confirm authenticity of a new criterion for microscopic malignancies' identification.