NOVEL APPROACHES TO THE SYMPTOMATIC TREATMENT OF PARKINSONIAN SYNDROMES - ALTERNATIVES AND ADJUNCTS TO DOPAMINE-REPLACEMENT

Authors
BROTCHIE JM
Citation
Jm. Brotchie, NOVEL APPROACHES TO THE SYMPTOMATIC TREATMENT OF PARKINSONIAN SYNDROMES - ALTERNATIVES AND ADJUNCTS TO DOPAMINE-REPLACEMENT, Current opinion in neurology, 10(4), 1997, pp. 340-345
Citations number
45
Categorie Soggetti
Neurosciences,"Clinical Neurology
Journal title
Current opinion in neurology → ACNP
ISSN journal
13507540
Volume
10
Issue
4
Year of publication
1997
Pages
340 - 345
Database
ISI
SICI code
1350-7540(1997)10:4<340:NATTST>2.0.ZU;2-I
Abstract
Advances in understanding basal ganglia function have suggested severa l nondopaminergic approaches to the treatment of parkinsonian symptoms . Data from studies in animal models of Parkinson's disease suggest th at it is realistic to believe that these approaches might have antipar kinsonian efficacy comparable to those of currently available dopamine -replacing agents and might not be associated with debilitating dyskin etic side-effects after prolonged treatment.