Ja. Connolly et al., SHOULD CRYOSURGERY BE CONSIDERED A THERAPEUTIC OPTION IN LOCALIZED PROSTATE-CANCER, Urologic clinics of North America, 23(4), 1996, pp. 623
Cryosurgical ablation of the prostate currently is under investigation
as a potential treatment for localized prostate cancer. Results to da
te indicate that the majority of patients have negative biopsies and a
marked reduction in prostate-specific antigen levels following cryoth
erapy. This treatment, however, is associated with significant side ef
fects, notably bladder outflow obstruction, impotence, and incontinenc
e, and its long-term durability is still unknown.