Conformational rigidity introduced by 2 ',5 '-phosphodiester links in DNA

Authors
Kumar, A Dass, D Atreyi, M Rao, MVR Katti, SB
Citation
A. Kumar et al., Conformational rigidity introduced by 2 ',5 '-phosphodiester links in DNA, NUCLEOS NUC, 20(10-11), 2001, pp. 1783-1796
Citations number
33
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN journal
15257770 → ACNP
Volume
20
Issue
10-11
Year of publication
2001
Pages
1783 - 1796
Database
ISI
SICI code
1525-7770(2001)20:10-11<1783:CRIB2'>2.0.ZU;2-Z
Abstract
Conformational properties of 2',5'-linked 3'-deoxyribonucleotides have been compared with their natural isomer using CD spectroscopy. It is inferred f rom the salt induced titration curves that the 2',5'-linked-3'deoxyribonucl eotides have rigid phosphodiester backbone.