The impact of endoscopic third ventriculostomy on the management of newly diagnosed hydrocephalus in infants

Objectives: To evaluate the role of endoscopic third ventriculostomy (ETV) as a primary treatment for hydrocephalus in children less than 1 year old a nd to determine its impact as a whole on the reduction of shunts necessary in a new population of hydrocephalic infants. Methods: Data were collected prospectively on 47 infants with newly diagnosed hydrocephalus of all aetio logies who were referred between 1st April 1998 and 30th September 2000. Tw enty-one patients (median age 6 weeks, range 34 weeks of gestation to 10 mo nths) underwent ETV, while the remaining 26 patients had insertion of a ven triculoperitoneal shunt. Anatomical criteria and demonstration of third ven tricle outflow obstruction on preoperative magnetic resonance imaging were used to select patients for ETV. Results: There was no mortality or major m orbidity following ETV. The median follow-up period was 18 (range 8-36) mon ths. During the follow-up period, the ETV remained patent in 7 (33%) of the 21 patients. Of the 14 patients with failed ETV, 11 had insertion of a ven triculoperitoneal shunt, while 3 have undergone successful redo ETV. Theref ore, in total 10 patients (48%) of the ETV group remain shunt independent. The best results were obtained in patients with congenital aqueduct stenosi s with 71% (5 of 7 patients) success rate, while patients with posthaemorrh agic hydrocephalus did particularly badly with only 1 of 10 patients having a successful ETV. Overall, 10 of 47 (21%) infants with newly diagnosed hyd rocephalus have avoided a shunt. Conclusions: Our results suggest that the selective use of ETV as the primary treatment in infants with hydrocephalus is safe and can lead to a reduction in the shunted population of all newly diagnosed hydrocephalic infants by up to 21%. Success of ETV is aetiology, not age dependent. Copyright (C) 2001 S. Karger AG, Basel.