The hydroxyanilide fenhexamid, a new sterol biosynthesis inhibitor fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea)

Citation
D. Debieu et al., The hydroxyanilide fenhexamid, a new sterol biosynthesis inhibitor fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea), PEST MAN SC, 57(11), 2001, pp. 1060-1067
Citations number
32
Categorie Soggetti
Entomology/Pest Control
Journal title
PEST MANAGEMENT SCIENCE
ISSN journal
1526498X → ACNP
Volume
57
Issue
11
Year of publication
2001
Pages
1060 - 1067
Database
ISI
SICI code
1526-498X(200111)57:11<1060:THFANS>2.0.ZU;2-V
Abstract
Fenhexamid, a recently developed botryticide, is shown here to inhibit ster ol biosynthesis. When the fungus Botryotinia fuckeliana was grown in the pr esence of fenhexamid, the ergosterol content was reduced, and three 3-keto compounds, 4 alpha -methylfecosterone, fecosterone and episterone, accumula ted, suggesting an inhibition of the 3-keto reductase involved in C-4 demet hylation. Thus, fenhexamid belongs to a new, promising class of sterol bios ynthesis inhibitors not previously used in agriculture or in medicine. (C) 2001 Society of Chemical Industry.