Cm. Baldwin et al., THE ASSOCIATION OF RESPIRATORY-PROBLEMS IN A COMMUNITY SAMPLE WITH SELF-REPORTED CHEMICAL INTOLERANCE, European journal of epidemiology, 13(5), 1997, pp. 547-552
This epidemiological study evaluated respiratory histories in those in
dividuals reporting chemical intolerance (CI) in a community populatio
n sample. The subsample of 181 completed standard Respiratory Health Q
uestionnaires. CI was determined from self-ratings of feeling 'moderat
ely' to 'severly' ill from exposure to at least three of five common c
hemicals (paint, pesticides, car exhaust, new carpet, and perfume); th
e prevalence rate was 22.7%. The comparison group (CN) (31.5% of the s
ample) were selected from their reports of 'never' feeling ill from th
e same chemicals. The prevalence rate of CI in females was over twice
that in males (28% vs 12.9%), a significant difference. There were no
significant differences in smoking, age, or education between CI and C
N. Prevalence rates for symptoms and Relative Risk Ratios (RR) indicat
ed that the CI were significantly more likely to report chronic cough,
phlegm, wheeze, chest tightness, exertional dyspnea, acute respirator
y illnesses, hay fever, child respiratory trouble, and physician confi
rmed asthma. Several of these respiratory symptoms were significantly,
though differentially, related to 'current' asthma and hay fever repo
rts. Results suggest a potential vulnerability to and greater interfer
ence from respiratory illness for the CI, which have implications for
women's health and quality of life.