For the diagnosis of liver cirrhosis ultrasound, computed tomography, magne
tic resonance imaging, and angiography are recommended as imaging modalitie
s. Ultrasound of the liver is used as a screening imaging tool in cases of
patients suspicious for diffuse liver disease and is helpful in the term of
follow-up examinations, Computed tomography is mainly performed to clarify
the presence of liver disease detected by ultrasound. In this context, acc
urate examination of the vascular structures of the liver as well as extrah
epatic situation, is of the essence. Diagnosis of diffuse liver disease and
characterization of morphologic changes is improved using contrast-enhance
d MR imaging with liver specific contrast media. Combined magnetic resonanc
e imaging can provide comprehensive evaluation of cirrhosis. An improved de
tection rate and characterization of regenerating nodules can be achieved c
ompared to imaging modalities such as ultrasound and computed tomography. M
R imaging can be performed in a one-stop-technique using unenhanced and liv
er-specific-contrast-enhanced sequence protocols to evaluate the liver pare
nchyma itself, MR cholangiography to verify the bile duct system, and MR an
giography to specify the vascular situation. This technique is the optimal
protocol for diagnostic imaging in patients suffering from liver cirrhosis
and the method of choice to reach the final diagnosis.