Synthesis of 19,B-bisnoranalogs of steroid androgens with cis-fused B and C rings

Authors
Egorov, MS Grinenko, EV Zorina, AD Balykina, LV Selivanov, SI Shavva, AG
Citation
Ms. Egorov et al., Synthesis of 19,B-bisnoranalogs of steroid androgens with cis-fused B and C rings, RUSS J ORG, 37(6), 2001, pp. 802-810
Citations number
16
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
10704280 → ACNP
Volume
37
Issue
6
Year of publication
2001
Pages
802 - 810
Database
ISI
SICI code
1070-4280(200106)37:6<802:SO1OSA>2.0.ZU;2-T
Abstract
Reduction by Birch procedure of 3-methoxy-B-nor-8-isoestra-1,3,5(10)-triene s followed by hydrolysis of reaction products furnished 19,B-bisnor-8,10-is oanalogs of steroid androgens. With the use of the correlation NMR spectros copy a complete assignment of signals in the H-1 and C-13 NMR spectra was p erformed for two representatives of this steroid group, and their prevailin g conformations in solution were established.