This paper describes the use of a microsphere sensor technology that allows
simple fabrication of vapor sensor arrays with reproducible response patte
rns. Microsphere sensor fabrication protocols are uncomplicated and yield b
illions of highly reproducible sensors. Microsphere sensor arrays combined
with a generalized Whitney-Mann-Wilcoxen (GWMW) classifier were used to dis
criminate between the presence and absence of nitroaromatic compounds in hi
gh background vapor mixtures. The classifier was trained on one sensor arra
y and then used to obtain 98.2 and 93.7% correct classification rates with
data collected using two subsequent arrays made up to six months after the
initial training was performed. These results represent an advance in the a
bility to transfer training data between multiple sensor arrays with a fluo
rescence-based artificial nose.