Inclusion body myositis associated with sacroidosis: a report of 3 cases

Inclusion body myositis (IBM) is a severe form of idiopathic inflammatory m yopothy, A predominantly T CD8+ lymphocytic infiltrate, with focally non-ne crotizing muscular fiber invasion, and rimmed-vacuoles are specific histolo gical signs, A few cases of IBM associated with other dysimmune diseases ha ve been reported, but only once with Systemic sarcoidosis. We report three cases of muscular sarcoidosis associated with IBM, This very uncommon obser vation suggests that major complex of histocompatibility, soluble factors, cytokines and adhesion molecules could be involved. Our cases are a novel e xample of associated dysimmune diseases.