Background. The aim of this study was to investigate the extent of reductio
n in maximum oxygen consumption in the early postoperative period after lun
g resection for lung carcinoma.
Methods. A total of 115 patients who underwent lung resection (95 lobectomi
es, 20 pneumonectomies) performed a maximal stair-climbing test the day bef
ore operation and the day of discharge from the hospital (8 +/- 3.3 days af
ter the operation).
Results. The postoperative test showed a 15% reduction in maximum oxygen co
nsumption ((V) over dot O(2)max) with respect to the preoperative test (Stu
dent's t test, p < 0.0001). This reduction was greater after pneumonectomy
(21.4%) than after lobectomy (14%) (Student's t test, p < 0.05). A multiple
regression analysis showed that the only significant independent predictor
s of both preoperative and postoperative (V) over dot O(2)max were the age
of the patient and the level of arterial oxygen content.
Conclusions. The early postoperative reduction in (V) over dot O(2)max was
greater after pneumonectomy than after lobectomy and the exercise performan
ce was significantly influenced by the level of arterial oxygen content bot
h before and early after the operation. (C) 2001 by The Society of Thoracic
Surgeons.