Twenty-five percent of primary hyperparathyroidism is caused by ectopic med
iastinal parathyroid glands, with 2% of these not accessible to standard ce
rvical surgical approaches. Advancement in video-assisted thoracoscopic sur
gical techniques has decreased the need for sternotomy to successfully remo
ve these ectopic glands. The thoracoscopic approach, however, is limited by
the surgeon's inability to, always accurately visualize ectopic glands. In
traoperative radionuclide-guided dissection, using a thoracoscopic approach
, provides a novel adjunct to the removal of occult ectopic parathyroid gla
nds. We report a case of an occult ectopic parathyroid adenoma removed thor
acoscopically using an intraoperative handheld gamma probe. (C) 2001 by The
Society of Thoracic Surgeons.