J. Jozwik et al., Asymmetric induction in the 1,3-dipolar cycloaddition of chiral nitrile oxide derived from (2R)-bornane-10,2-sultam, CHIRALITY, 13(10), 2001, pp. 629-630
The efficient preparation of the chiral nitrile oxide derived from N-glyoxy
loyl-(2R)-bornane-10,2-sultam is presented. The nitrile oxide was trapped i
n situ with substituted olefins as dipolarophiles to furnish optically acti
ve 2-isoxazolines. (C) 2001 Wiley-Liss, Inc.