Profound T-lymphocytopenia and cryptococcemia in a human immunodeficiency virus-seronegative patient with disseminated tuberculosis

Authors
Zaharatos, GJ Behr, MA Libman, MD
Citation
Gj. Zaharatos et al., Profound T-lymphocytopenia and cryptococcemia in a human immunodeficiency virus-seronegative patient with disseminated tuberculosis, CLIN INF D, 33(11), 2001, pp. E125-E128
Citations number
14
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
10584838 → ACNP
Volume
33
Issue
11
Year of publication
2001
Pages
E125 - E128
Database
ISI
SICI code
1058-4838(200112)33:11<E125:PTACIA>2.0.ZU;2-4
Abstract
A 47-year-old human immunodeficiency virus-seronegative West African man wh o presented in extremis with cachexia, lymphadenopathy, multiple organ dysf unction, and marked T-lymphocytopenia received the diagnosis of disseminate d tuberculosis, cryptococcal pneumonia, and cryptococcemia. His subsequent course and our review of the literature suggest that the profound T-lymphoc ytopenia and ensuing cryptococcal disease were likely attributable to disse minated tuberculosis.