Gene and genome duplication

Authors
Citation
D. Sankoff, Gene and genome duplication, CUR OP GEN, 11(6), 2001, pp. 681-684
Citations number
48
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN GENETICS & DEVELOPMENT
ISSN journal
0959437X → ACNP
Volume
11
Issue
6
Year of publication
2001
Pages
681 - 684
Database
ISI
SICI code
0959-437X(200112)11:6<681:GAGD>2.0.ZU;2-5
Abstract
Genomic sequencing projects have revealed the productivity of processes dup licating genes or entire chromosome segments. Substantial proportions of th e yeast, Arabidopsis and human gene complements are made up of duplicates. This has prompted much interest in the processes of duplication, functional divergence and loss of genes, has renewed the debate on whether an early v ertebrate genome was tetraploid, and has inspired mathematical models and a lgorithms in computational biology.