In the face of the growing worldwide prevalence of type 2 diabetes, effecti
ve methods of preventing further increases in prevalence are needed. In thi
s paper, we review the community-based epidemiologic studies of diabetes in
Taiwan published during the last decade, and look at the effectiveness of
a two-stage screening protocol for identifying subjects at risk for progres
sion to type 2 diabetes. The results of these studies indicate that the age
-adjusted prevalence rate of undiagnosed diabetes in Taiwan is stable, at a
round 4.0%, while the annual incidence rate is about 1.8%. The results of s
everal studies strongly suggest that a two-step screening strategy, in whic
h only subjects with a fasting plasma glucose level of 5.6-7.8 mmol/l recei
ve the oral glucose tolerance test, may be an effective means of identifyin
g diabetics and persons at high risk for progression to type 2 diabetes and
, ultimately, slowing the increase in the prevalence of this disease. (C) 2
001 Elsevier Science Ireland Ltd. All rights reserved.