IS FAMILIAL COMBINED HYPERLIPIDEMIA A GENETIC DISORDER OF ADIPOSE-TISSUE

Authors
ARNER P
Citation
P. Arner, IS FAMILIAL COMBINED HYPERLIPIDEMIA A GENETIC DISORDER OF ADIPOSE-TISSUE, Current opinion in lipidology, 8(2), 1997, pp. 89-94
Citations number
34
Categorie Soggetti
Biology,"Peripheal Vascular Diseas
Journal title
Current opinion in lipidology → ACNP
ISSN journal
09579672
Volume
8
Issue
2
Year of publication
1997
Pages
89 - 94
Database
ISI
SICI code
0957-9672(1997)8:2<89:IFCHAG>2.0.ZU;2-H
Abstract
Familial combined hyperlipidaemia is a common cause of coronary heart disease. Its aetiology is heterogeneous. The genetic and metabolic bas is of the disorder has not yet been defined. This review discusses the putative role of adipose tissue in the pathogenesis of familial combi ned hyperlipidaemia. It is possible that mutations in genes regulating the turnover of lipids in fat cells are involved in the aetiology.