The association between depressive symptoms and 2 measures of HIV disease s
tatus in 73 African American single mothers was examined. Hierarchical mult
iple regression analyses revealed that clinician-rated depressive symptoms
predicted subjective, but not objective, parameters of disease status 12 to
14 months later. More symptoms of depression at the Ist assessment predict
ed an increase in physical complaints over the course of the study. Results
suggest that researchers and clinicians interested in enhancing quality of
life among African American single mothers with HIV infection, an understu
died population within the HIV-AIDS literature, should consider both subjec
tive and objective measures of the disease.