12H-[2]-benzothiepino[6,5a,5-bc]benzofuran: Synthesis of a sulfur-analog of galanthamine

Citation
M. Treu et al., 12H-[2]-benzothiepino[6,5a,5-bc]benzofuran: Synthesis of a sulfur-analog of galanthamine, HETEROCYCLE, 55(9), 2001, pp. 1727
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
55
Issue
9
Year of publication
2001
Database
ISI
SICI code
0385-5414(20010901)55:9<1727:1SOASO>2.0.ZU;2-8
Abstract
An analog of the anti-Alzheimer drug galanthamine, carrying a SO2-moiety in stead of an amino-functionality, has been synthesized as a racemic mixture using tandem cyclization techniques to form a new four membered heterocycli c ring system.