A convenient route to the soluble guanylate cyclase activator YC-1 and itsN2 regioisomer

Authors
Fernandez, PA Bellamy, T Kling, M Madge, DJ Selwood, DL
Citation
Pa. Fernandez et al., A convenient route to the soluble guanylate cyclase activator YC-1 and itsN2 regioisomer, HETEROCYCLE, 55(9), 2001, pp. 1813
Citations number
18
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
03855414 → ACNP
Volume
55
Issue
9
Year of publication
2001
Database
ISI
SICI code
0385-5414(20010901)55:9<1813:ACRTTS>2.0.ZU;2-H
Abstract
A new route to the soluble guanylate cyclase (sGC) activator YC-1 and its N 2 regioisomer has been established with a Mitsunobu mediated N-alkylation a s the key step. The route is utilised in the synthesis of a potential photo affinity label.