An infection with Ehrlichia phagocytophila, the agent of tickborne fev
er, can cause abortion or stillbirth in cows in late pregnancy but, to
the authors' know-ledge, there have been no reports of intrauterine i
nfection in cows followed by clinical signs in the calf, To study the
effect of E phagocytophila on the fetus, a cow was infected experiment
ally after 270 days of pregnancy, It developed the clinical and haemat
ological signs characteristic of tickborne fever six days after infect
ion. At 287 days of pregnancy the cow gave birth to a live calf, which
became ill at 13 days of age. The general condition and behaviour of
the calf were only mildly affected but it had a high temperature and s
wollen prescapular lymph nodes, Its appetite and suck reflex remained
normal. E phagocytophila inclusion bodies were visible, predominantly
in neutrophils and eosinophils, for seven days, The calf seroconverted
, as detected by indirect immunofluorescence, 14 days after it became
ill.