Conjugated linoleic acid reduces body fat in healthy exercising humans

This study was designed to investigate the efficacy and tolerability of dai ly conjugated linoleic acid (CLA) in healthy exercising humans. This was a randomized, double-blind, placebo-controlled study in 20 healthy humans of normal body weight and body mass index less than 25.0 kg/m(2), who did stan dardized physical exercise in a gym for 90 min three times weekly. Particip ants took either placebo (hydrogel) or CLA 0.6 mg, three times daily, as tw o capsules during meals, for 12 weeks. Body fat, measured using near infrar ed light, was significantly reduced in the CLA group during the study, but not in the placebo group. No effects on body weight were observed. Tolerabi lity was good and similar in the two groups. Compliance, as judged by the n umber of returned capsules, was more than 80% of the recommended dose for a ll participants. Thus CLA reduces body fat but not body weight in healthy e xercising humans of normal body weight.