Histomorphometric study of growth plate subjected to different mechanical conditions (compression, tension and neutralization): An experimental studyin lambs - Mechanical growth plate behavior
F. Arriola et al., Histomorphometric study of growth plate subjected to different mechanical conditions (compression, tension and neutralization): An experimental studyin lambs - Mechanical growth plate behavior, J PED ORT B, 10(4), 2001, pp. 334-338
We studied the morphologic effect of low mechanical stresses (compression,
tension and neutralization) on the growth cartilage with an external fixato
r in IS young lambs. On radiography, we only found more length in the femor
a subjected to tension (P < 0.05). Bony bridges were not present, nor were
there signs of altered vascularization or Ranvier's perichondral ring. Hist
omorphometrically, in the group subjected to tension, the germinative layer
in the femur was higher (P < 0.001) in the bones that had undergone surger
y. The proliferative layer was lower in the operated tibia (P < 0.001), and
the hypertrophic layer was higher in operated tibias and femora (P < 0.001
). In the group subjected to compression, the germinative layer in the femo
ra was higher in the operated bones (P < 0.05); the proliferative layer of
the tibia was lower (P < 0.001) and the hypertrophic layer was higher (P <
0.001) in both operated bones. In the neutralization group, the proliferati
ve layer of both operated bones presented lower values (P < 0.001) and the
hypertrophic layer was higher (P < 0.001) than that in the control groups.