The comparative cervical skin test for antemortem diagnosis of tuberculosis
was done 169 times on 116 different white-tailed deer of known Mycobacteri
um bovis infection status. The sensitivity and specificity were 97 and 81%,
respectively. The magnitude of change in skin thickness at test sites was
not significantly influenced by dosage of inoculum, dissemination of the di
sease process, or repeated skin testing. However, the magnitude of change i
n skin thickness was significantly greater in deer infected for less than 1
09 days than in deer infected for more than 109 days. As used in the presen
t study, the comparative cervical skin test is a sensitive method of antemo
rtem diagnosis of M. bovis infection in white-tailed deer.