Nutritional factors and Alzheimer's disease

Authors
Reynish, W Andrieu, S Nourhashemi, F Vellas, B
Citation
W. Reynish et al., Nutritional factors and Alzheimer's disease, J GERONT A, 56(11), 2001, pp. M675-M680
Citations number
64
Categorie Soggetti
Public Health & Health Care Science","Medical Research General Topics
Journal title
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
ISSN journal
10795006 → ACNP
Volume
56
Issue
11
Year of publication
2001
Pages
M675 - M680
Database
ISI
SICI code
1079-5006(200111)56:11<M675:NFAAD>2.0.ZU;2-3
Abstract
Nutritional factors are integrally linked with Alzheimer's disease (AD). Al though AD patients have no changes in energy metabolism, fluctuations in we ight are fairly common. The potential role of vitamin B-12 and folate, with the production of hyperhomocysteinemia, in the pathophysiology of AD is ex plored. The role of free-radical damage in AD is discussed. It is stressed that alterations in dietary lipids may play an important role in cognitive defects in AD secondary to their effects on neuronal membrane lipids. More research is needed on the role of nutrition in the ongoing development of c ognitive changes in AD.