Jt. Reed et al., TREATMENT OF PERIORBITAL WRINKLES - A COMPARISON OF THE SILKTOUCH CARBON-DIOXIDE LASER WITH A MEDIUM-DEPTH CHEMICAL PEEL, Dermatologic surgery, 23(8), 1997, pp. 643-648
BACKGROUND. Chemical peels are an effective treatment for wrinkles, bu
t their use is limited because of the associated risk of scarring, hyp
opigmentation, and the inability to accurately control the depth of ti
ssue injury. High energy, pulsed, or computer scanned continuous wave
carbon dioxide (CO2) lasers cause minimal thermal injury, decrease the
risk of scarring, and allow for precise control of tissue vaporizatio
n to predictable depths. OBJECTIVE. To compare the effectiveness and s
ide effect profile of a medium-depth chemical peel to that of the Silk
Touch CO2 laser in the treatment of periorbital wrinkles. METHODS. Twe
nty-four subjects (nine male, 15 female) with moderate to severe perio
orbital wrinkles were assigned a wrinkle score (1 = mild through 5 = s
evere) before treatment and 6 months after treatment. Each subject was
treated with Jessner's solutin and 35% trichloroacetic acid on one si
de and the Silk-Touch CO2 laser on the other side. RESULTS. The averag
e periorbital wrinkle score decreased from 4.00 +/- 0.78 before laser
treatment to 1.75 +/- 0.68 6 months after treatment. The chemical peel
wrinkle score decreased from 4.13 +/- 0.85 to 3.29 +/- 0.99. The degr
ee in which the wrinkle score improved after laser treatment compared
with after chemical peel treatment was statistically significant. Post
treatment erythema lasted an average of 4.5 months for the laser-treat
ed areas and 2.5 months for the chemical peel-treated areas. CONCLUSIO
N. Treatment of periorbital wrinkles with the Silk-Touch CO2 laser res
ulted in a greater degree of improvement than treatment with a medium-
depth chemical peel but had longer lasting posttreatment erythema. (C)
1997 by the American Society for Dermatologic Surgery, Inc.