A. Rosenbach et Ts. Alster, MULTIPLE TRICHOEPITHELIOMAS SUCCESSFULLY TREATED WITH A HIGH-ENERGY, PULSED CARBON-DIOXIDE LASER, Dermatologic surgery, 23(8), 1997, pp. 708-710
BACKGROUND. Multiple trichoepitheliomas are transmitted in an autosoma
l dominant fashion and can be clinically disfiguring. As with other de
rmal tumors, destructive techniques such as cryotherapy, electrodesicc
ation, and radiation therapy can improve the cosmetic appearance, but
each of these treatments carries a significant risk of side effects an
d recurrence. OBJECTIVE. We describe a patient with a severe case of r
ecurrent multiple trichoepitheliomas following excision, cryotherapy,
and electrodessication. RESULTS. Treatment with a high-energy, pulsed
carbon dioxide laser produced an excellent clinical response with no r
ecurrence noted in the treated area for 12 months. CONCLUSION. Laser v
aporization of trichoepitheliomas using a pulsed carbon dioxide delive
ry system may provide superior clinical results without scanning and e
vidence of regrowth. (C) 1997 by the American Society for Dermatologic
Surgery, Inc.