Ml. Sharma et Tek. Chand, SYNTHESIS OF (+ THYL-6-(3'-HYDROXY-4'-METHYLPHENYL)-2-HEPTEN-4-ONE [TURMERONOL-A]/, Proceedings of the Indian Academy of Sciences. Chemical sciences, 109(3), 1997, pp. 177-180
The first total synthesis of the racemic title compound is described.
3-Hydroxy-4-methyl acetophenone was used as the starting material and
transformed into the target molecule in six steps. Synthetic turmerono
l A displays spectral properties similar to those reported for the nat
ural compound leading to confirmation of the proposed structure.