Ma. Adams et al., VASCULAR CONTROL MECHANISMS IN PENILE ERECTION - PHYLOGENY AND THE INEVITABILITY OF MULTIPLE AND OVERLAPPING SYSTEMS, International journal of impotence research, 9(2), 1997, pp. 85-91
A co-ordinated series of vascular events underlie the generation of a
penile erection. The control and regulation of this simple event is, i
n fact, a complex of interactions occurring at multiple levels. Many o
f these individual pathways and responses have been studied extensivel
y. The understanding of the necessity for the integration between the
individual pathways into a complex of series and parallel coupled mech
anisms provides a rationale for the development of a framework of mult
iple and overlapping systems. This paper sets out some of the principl
es of integrated and balanced control of vasodilation and vasoconstric
tion in the penis. In addition, the role of growth induction and regre
ssion and the importance of time as a factor in studying penile struct
ure and function is discussed.